Logo Leibniz Universität Hannover
Logo: Hannover Center of Mechatronics/Leibniz Universität Hannover
Logo Leibniz Universität Hannover
Logo: Hannover Center of Mechatronics/Leibniz Universität Hannover
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Completed Projects in Medical Engineering

Medical Engineering

Debulking From Within: A Steerable Needle for Intracerebral Hemorrhage Aspiration

Bild zum Projekt Minimal-invasive Evakuation von intrazerebralen Blutungen (ICB)

Supervisor:

Dr.-Ing. Jessica Burgner-Kahrs

Duration:

09/2014-08/2016

Funded by:

National Institutes of Health (NIH) R21

Brief description:

In collaboration with Vanderbilt University, Nashville, USA we are developing a robot system for minimally-invasive intracebral hemorrhage evacuation in the scope of this NIH R21 project. The goal is to approach the hemorrhage through a small borehole in the skull with an active cannula and to debulk it from within by coordinated movements of a prebend aspiration cannula. The subproject of our research group CROSS is concerned with effecient motion planning techniques for aspiration of arbitrary hemorrhage geometries. The challenge is to develop adaptive motion planning methods that allow for real-time changes in the hemorrhage geometry during the procedure.

 

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Development of Biocompatible Magnesium Alloys and Investigations into their Degradation Behaviour

Bild zum Projekt Entwicklung von biokompatiblen Magnesiumlegierungen und Untersuchung von deren Degradationsverhalten

Researcher:

IW

Duration:

until 2014

Funded by:

DFG - SFB 599

Brief description:

This research project deals with the development of an alloy for degradable implants based on magnesium. These implant materials shall be suitable for use in hard tissue (high strength) as well as in soft tissue (high ductility). The degradation process adapted to the component and its implantation area is adapted by different coatings and various material combinations. The alloys are tested in in-vitro and ex-vivo test systems concerning their biocompatibility in different types of tissues and are then transferred into in-vivo systems. Applications are for example paranasal sinus stents.

 

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Sonification-based Motoric Rehabilitation

Bild zum Projekt Sonifikationsbasierte motorische Rehabilitation

Researcher:

IMS, Institute of Sports Science, Hannover University of Music, Drama and Media, Co. KIND, Co. videantis

Duration:

since 2011

Funded by:

EFRE, EU & Land Lower Saxony

Brief description:

Within the scope of this joint research project, the IMS investigates possible hardware platforms for sonification of motion data, which can be used in medical rehabilitation, e.g. for stroke patients. By this means, the rehabilitation time for relearning motion patterns shall be reduced. Important parameters for mobile hardware platforms are their weight, battery life and sufficient computing power. The research at IMS focuses on hardware platforms for real-time mobile capturing, processing and sonification of complex motion data.

 

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Robot-assisted Laser Osteotomy

Bild zum Projekt Roboterassistierte Laserosteotomie

Researcher:

imes

Duration:

since 2011

Funded by:

KUKA Laboratories GmbH

Brief description:

Laser osteotomy is of great interest for many clinical indications. Tissue removal following well defined geometries raises questions primarily in the fields of path planning, high-precision beam control, human-machine interface and determination of cutting depth. Therefore, a system consisting of a KUKA lightweight robot (LWR), a stereo camera, an optical coherence tomograph (OCT), and an Er:YAG laser is assembled at the Institute of Mechatronic Systems in close cooperation with the KUKA Laboratories GmbH to demonstrate a possible application for robot-assisted laser osteotomy.

 

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Development of Instruments for Laparoscopic Surgery

Bild zum Projekt Entwicklung chirurgischer Instrumente für die Laparoskopie

Researcher:

imes

Duration:

since 2010

Funded by:

Richard Wolf GmbH

Brief description:

For minimally invasive surgery (MIS), instruments are inserted into the abdominal cavity of the patient through small incisions. In order to make these procedures easier and safer - even for complicated manipulations such as knot tying - novel surgical instruments are needed. They offer more degrees of freedom inside the patient and are controlled by an intuitive console. The aim of the project is to develop these adequate instruments with at least two degrees of freedom.

 

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Determination of Drawing Parameters and Production of Resorbable Suture Materials Based on Magnesium

Bild zum Projekt Entwicklung der Ziehparameter und Herstellung resorbierbarer Nahtmaterialien auf Magnesiumbasis

Researcher:

IW, AGH Krakau

Duration:

2009 - 2011

Funded by:

DFG

Brief description:

Aim of the project is to investigate all aspects concerning drawing magnesium wires. The main research focus is laid on magnesium alloys with an improved biocompatibility, since one possible application of magnesium wires is their use as bioresorbable suture material for medical purposes. The investigations comprise the complete process chain from the alloy casting process over extrusion processes for the manufacturing of pre wire materials towards the evaluation of the influence of various drawing parameters.

 

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Active Micro-optics

Bild zum Projekt Aktive Mikrooptiken

Researcher:

IMPT

Duration:

sincs 2009

Funded by:

DFG

Brief description:

Within the framework of the project „Electromagnetic Actuation of Micro-optics: Adaptive Systems on the basis of Ferro fluidic Actuators“ of the SPP 1337 „Active Micro-optics“, the Institute of Micro Production Technology (IMPT) deals with the design and production of a micro actuator. By excitation of the micro coil array as part of the micro actuator, an electromagnetic field is induced, displacing a ferrofluid in a micro channel. By moving the electromagnetic liquid body, an optically active liquid is displaced within the fine micro channel structures made of PMMA. To model the micro coil array, FEM analyses were successfully carried out for simulation of the magnetically excited field and the temperature. From the simulation results, the design for the lithographic photo masks was derived. Then a process chain was developed for the micro actuator production, and the corresponding thin-film processes were optimised. In the meantime, the first actuators have already been produced, and the experiences gained have been used for design optimisation. The first optimised micro actuators are now completed and under test. In the subsequent system integration phase, two micro actuators form a sandwich structure with the micro channel structure in the middle.

 

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Inner Ear Micro Actuator for the Excitation of the Perilymph in case of Hearing Problems

Bild zum Projekt Innenohrmikrowandler zur Anregung der Perilymphe bei Schwerhörigkeit

Researcher:

IMPT, MHH

Duration:

2008 - 2012

Funded by:

DFG

Brief description:

Aim of the project is to develop a micro system which can be implanted in order to improve hearing. For this purpose, an electromagnetic micro actuator excites via the round window membrane the perilymph of the cochlea. Possible applications are medium labyrinthine hearing loss, conductive deafness and combined labyrinthine hearing loss. The prerequisites for this project are a high degree of biocompatibility and reliability and a simple handling during surgery. The project is realised in cooperation with the Hannover Medical School.

 

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Medical Image Processing

Bild zum Projekt Medizinische Bildverarbeitung

Researcher:

TNT

Duration:

2007 - 2010

Funded by:

Philips

Brief description:

In case of an automated image-based analysis of the spinal column used for many orthopedic applications, an exact segmentation of the individual vertebras is the basis. The spinal column is of great interest, because the scanned image area can be identified via the individual vertebras. In order to extract the relevant information from the image data obtained via computer tomography (CT), previous knowledge is needed. One approach for an automated analysis of medical image data is therefore the use of anatomic models. In Philips research laboratories in Hamburg, surface models of all presacral vertebras are developed and integrated in the segmentation process.

 

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Enhancement of Magnesium Structures to Support Cardiovascular Tissue Replacement in the High-pressure System

Bild zum Projekt Stabilisierende Magnesiumgeflechte zur Unterstützung von kardiovaskulärem Gewebeersatz im Hochdrucksystem

Researcher:

IW, IKM, MHH-LEBAO

Duration:

2007 - 2014

Funded by:

DFG - SFB599

Brief description:

In cardiovascular surgery, rehabilitative surgery methods for valvular and vascular transplants as well as for heart muscle damage are state-of-the-art. Decellularised tissue which is recolonised by incorporation of the receiver‘s own cells, having growth potential without being immunogenic, has already been used successfully in cardiovascular low-pressure systems. Goal of this project is the development of magnesium structures to support cardiovascular tissue replacement in the high-pressure system of the left chamber of the heart and the aorta.

 

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Image-based Automated Insertion of Cochlear Implants

Bild zum Projekt Optisch kontrollierte, automatisierte Insertion einer Cochlear Implant Elektrode

Researcher:

imes

Duration:

2006 - 2008

Funded by:

Deutsche Forschungsgemeinschaft (DFG)

Brief description:

The Institute of Mechatronic Systems developed a robot-assisted, minimal-invasive approach to the cochlea, drilling a small channel from the lateral skull base to the cochlea. In this context, the problem arises to insert the electrode into the cochlea via the keyhole access, which is not manually applicable by the surgeon any more. Main target of the project is the development of an automated insertion tool to insert the electrode via the keyhole access. The project is carried out in cooperation with the Department of Otolaryngology of the Hannover Medical School (MHH).

 

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